Notable features of and by the river are (North to South):
- Belle Isle island with the CyberLife Tower
- Kamski's house
- Ambassador Bridge
- Riverside Park
- "Banks of Detroit River, Delray" and "Banks of Detroit River, Canada"
- Gordie Howe International Bridge
Battle for Detroit Edit
If Kara was not able to get on the bus and did not steal the tickets from the family at the Bus Terminal. Adam will call them over and Rose will drive her car to the river. Rose will greet the android smuggler, who is her contact in smuggling androids. He has been waiting for Rose and he will ask for the money for the boats. Rose will give him the money and he will warn her about the border patrol is patrolling the area and tells her to tell the androids not to start the boat when further in the river. The smuggler will then leave. Rose and Adam will say goodbye to the others and leave. Kara, Alice and Luther (if alive) will talk about what will they do once they get into Canada. Then, U.S. Coast Guard boats will open fire on the boats and other androids will die. Kara, Alice and Luther (if alive) can take cover and the boats will stop firing. Luther will be hit by the gunfire. The boat will be leaking water and Kara will have to reduce the weight of the ship and push a deactivated Luther off the ship. Kara will have to push the boat to Canada.
- The river flows for 24 nautical miles (44 km; 28 mi) from Lake St. Clair to Lake Erie as a strait in the Great Lakes system and forms part of the border between Canada and the United States.
- In the real world, from the vantage point of Detroit, the Detroit River runs from west to east, with Detroit on the north side and Canada on the south side.